COVID-19: vaccines and contraindications

Many people have chronic diseases, allergies and other pathologies in modern life. And some of them are a “mediotok” from “antikovidny” vaccination. The truth is, which ones are almost not specified in the popular media. While a contraindication becomes a reason for increased alertness to infection, an obstacle to receiving a QR code and a reason for many restrictions.

Absolute
In one of our articles, we have already mentioned the peculiarities of the “structure” of anticoid vaccines (article “Comparison of vaccines”), which cause different reactogenicity.

Despite the different mechanism of action, the general contraindications to vaccination remain the same for all existing drugs. And a “permanent” (and not temporary) medical exemption from vaccination is issued in the event of:

critical allergic reactions to previous vaccinations (Quincke’s edema, anaphylactic shock, polymorphic exudative eczema and others),
hypersensitivity to vaccine components (for example, aluminum hydroxide, which is part of EpiVacCorona),
pregnancy,
breastfeeding
under 18 years of age (at the time of this writing, due to the lack of data on the efficacy and safety of vaccines in this group of patients),
acute vascular reactions to any vaccine at the time of vaccination (collapse, shock-like conditions) recorded in the patient’s medical record
A medical removal from the second “dose” is indicated if after the introduction of the first there were: fever over 40C, convulsions, anaphylactic shock, collapse, edema at the injection site with a diameter of more than 8 cm (in particular for “KoviVac”) and other recorded severe reactions after the first vaccination …

Temporary
Temporary contraindications include:

acute period of any infectious (including ARVI)
non-infectious (severe injuries, burns, operations and others) inflammatory processes,
period of exacerbation of chronic diseases,
vaccination in which should be postponed for at least 2-4 weeks (at least 4 weeks for EpiVacCorona) after recovery or complete remission.

And with a mild course of ARVI, as well as acute intestinal infections, you can get vaccinated within a few days after the temperature has returned to normal.

Relative
Vaccination can be done with caution by those who have:

chronic liver and kidney diseases,
severe disorders of the pituitary gland and hypothalamus,
severe pathologies of the hematopoietic system (significant deviations in the level and functioning of erythrocytes, leukocytes, platelets),
diseases of the central nervous system (epilepsy, recent stroke),
cardiovascular (coronary heart disease, endocarditis, pericarditis, myocarditis),
bronchopulmonary (chronic obstructive pulmonary disease, bronchial asthma, fibrosing alveolitis and others),
digestive (malabsorption syndrome, Crohn’s disease and others)
and endocrine systems (decompensation of diabetes mellitus, severe thyroid disorders and the like),
as well as immune disorders (allergic and autoimmune diseases).
And the final decision in favor of vaccination or medical treatment remains at the discretion of the attending physician, correlating the risk of potential infection with the risk of probable complications from vaccination.

BERLIN, GERMANY – MARCH 10 :Symbol photo of the coronavirus crisis. Diagnosis. COVID-19, SARS-CoV-2 on March 10, 2020 in Berlin, Germany. Health authorities around the world are concerned about the novel coronavirus. More and more countries are reporting diseases and new infections. (Photo by Thomas Imo/Photothek via Getty Images)

For people with autoimmune diseases and malignant neoplasms, the use of vaccines may be associated with special risks, due to the stimulation of the immune system and an unpredictable response to the latter. However, due to the lack of data on the percentage probability and nature of post-vaccination complications in such patients, the decision on vaccination is still at the discretion of the attending physician.

It is possible not to be vaccinated for those who, after a previous infection, have IgG antibodies to the S1 protein of the coronavirus. For at least 6 months from the date of the “documented” infection.

Well, if the antibodies are asymptomatic, the question of the need for vaccination is decided individually, depending on the nature of the patient’s work.

special instructions
There are not many such vaccines available today, namely:

in patients receiving immunosuppressive therapy or suffering from immunodeficiency conditions, the immune response to vaccination may not be sufficient. Therefore, the use of immunosuppressive drugs, if possible, is recommended to be canceled for 1 month before and after the planned vaccination;
and the vaccine of choice could be CoviVac, since the use of killed whole virion vaccines is not contraindicated in this case.
In addition, the use of most vaccines still has a strict age range – from 18 to 60 years. And only in relation to “Sputnik V” such restrictions are not provided, and the vaccine https://en.wikipedia.org/wiki/COVID-19_vaccine is recommended, including in patients over 60 years old.

It is noteworthy that not a single instruction for vaccines contains direct contraindications for people with clotting disorders.

In the meantime, for those who have a burdened heredity or risk factors for thrombosis, it is recommended to check the blood for “clotting” and assess the genetic predisposition to thrombosis before going on vaccination.

Of course, the annotation to vaccines is not yet complete and will be supplemented as observations accumulate.